Guerendo, as a potential depth option behind Robinson, could see additional looks if McCaffrey is limited. His role would be contingent on game plan and backup needs, offering a dart-throw flex in deeper fantasy formats.

Guerendo sits behind McCaffrey but could carve a downfield role if CMC is limited. As a TD-heavy or standard-format flyer, Guerendo offers upside in Week 1 and a potential mid-season breakout with SF’s committee usage. He’s a high-risk, high-reward option for deeper leagues and DFS tournaments.

Guerendo (SF) is a deep-league flex candidate behind CMC; his Week 1 relevance hinges on McCaffrey’s status. If CMC sits, Guerendo can step into a larger role, particularly in deeper leagues.

Guerendo is spotlighted as a Week 1 option behind an ailing Christian McCaffrey. In limited 30+ snap games he posted strong per-game numbers (17.9 PPR), suggesting upside if he gets extended touches due to McCaffrey’s calf issue. Behind Brian Robinson, Guerendo could emerge as a viable RB3/flex in deep leagues should McCaffrey sit. If McCaffrey plays, Guerendo’s role dips, relegating him to a speculative bench play.

Guerendo is highlighted as part of SF’s three-back Week 1 approach if McCaffrey’s availability is confirmed, offering a potential change-of-pace option. His role is mostly speculative, but he’s on the radar for late-season fantasy depth and in deeper leagues.